James Cook III
NFL Injury Report

James Cook III Injury Status

Buffalo Bills • RB
Latest Injury Status
active
A

The Bills rested most of their projected regular-season starters, so Cook's absence was expected. The star running back finished the preseason slate having appeared in one game, logging 21 yards on five carries. Cook now will look ahead to Week 1, when he's slated to lead Buffalo's backfield against a tough Texans defense on Sunday, Sept. 13. Ray Davis is expected to work as his top backup.

Injury Details

Body Part
Location
Side
Expected Return
Not announced

Betting Research

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James Cook III Injury History

August 30, 2026
active
Cook didn't play during Buffalo's exhibition win over Pittsburgh on Thursday.
August 29, 2026
active
Cook carried the ball five times for 21 yards in Saturday's 29-14 preseason win over the Panthers.

Latest James Cook III Injury Updates

This page tracks available injury information for James Cook III, including reported status, injury details, expected return information and updates that may be relevant when evaluating NFL betting markets.

Injury designations can change close to game time. Check the latest market prices and confirmed player availability before placing a wager.